Clinical, genetic, and pathological features of male pseudohermaphroditism in dog
1 Faculty of Veterinary Medicine, Department of Animal Health, Parma, Italy
2 Private Clinics, Parma, Italy
3 Faculty of Agronomy, Department of Animal Science, Milan, Italy
4 University of Veterinary Medicine Hannover, Department of Pathology, Germany
Reproductive Biology and Endocrinology 2011, 9:12 doi:10.1186/1477-7827-9-12Published: 21 January 2011
Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.