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Table 1
Effect of ovarian cycle on HPA axis response to acute stress.
Species	Stressor	Phase of the cycle	HPA axis response	References

Rats	Surgery	On the morning of proestrus	Positive	[38]
	20-min restraint	On the morning of proestrus vs either estrus or diestrus	Increased	[39]
		Proestrus, estrus and diestrus II	No cycle effect	[40]
Rhesus monkeys	30-min intracerebroventricular administration of interleukin-1α	Mid-follicular vs early-follicular phase	Increased	[41]
Women	Bilateral ovariectomy plus total hysterectomy	Mid- to late-follicular phase	Positive	[43]
		Early- to mid-luteal phase	No response	[42,43]
	Cholecystectomy	Early- to mid-follicular phase	Positive	[42]
	20-min progressive submaximal treadmill exercise	Mid-luteal phase vs early follicular phase	Increased	[44]
	90-min submaximal bicycle exercise	Mid-luteal phase vs mid-follicular phase	Increased	[46]
	90-min submaximal treadmill exercise	Mid-luteal phase vs early- and late-follicular phase	Increased	[47]
	60-min progressive submaximal treadmill exercise	Mid-follicular and luteal phase	No cycle effect	[49]
	Progressive maximal treadmill exercise to voluntary exhaustion or 40-min submaximal treadmill exercise	Early-follicular vs mid-luteal phase	No cycle effect	[50]
	20-min progressive submaximal aerobic treadmill	Early-mid-follicular, periovulatory and mid-late luteal phase	No cycle effect	[51]
	Psychological stress of remembering stressful situations in their lives and self-evaluation	Menstrual and periovulatory (late-follicular, ovulatory and early-luteal phases) phase	No cycle effect	[52]
	Psychological stress of self-evaluation	Ovulatory period vs premenstrual phase	Decreased	[48]

Tarín et al. Reproductive Biology and Endocrinology 2010 8:53 doi:10.1186/1477-7827-8-53

Table 1