Determinants of menarche
Third Department of Pediatrics, University of Athens School of Medicine, "Attikon" University Hospital, Haidari, Athens 12462, Greece
Reproductive Biology and Endocrinology 2010, 8:115 doi:10.1186/1477-7827-8-115Published: 30 September 2010
Menarche is a milestone in a woman's life as it denotes the start of reproductive capacity. Aim of this report is to review the recent developments and the current knowledge in the neuroendocrinology of pubertal onset and the factors, genetic and environmental, that influence menarcheal age. We also review the implications of early or late menarcheal age on a young woman's life.