Figure 3.

Secretion of steroid hormones (A. Estradiol; B. Progesterone and C. Testosterone), obtained from conditioned media from cultured follicles over 12 days in the absence (Dark blue circles) or presence of Sema-4D (Pink square) or in combination with specific neutralizing antibodies against Plexin-B1 (turquoise triangles). The graph represents mean ± SEM of the steroid hormones secreted from three independent experiments in triplicate.