Open Access Highly Accessed Review

The prolactin and growth hormone families: Pregnancy-specific hormones/cytokines at the maternal-fetal interface

Michael J Soares

Author Affiliations

Institute of Maternal-Fetal Biology, Division of Cancer & Developmental Biology, Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, Kansas 66160, USA

Reproductive Biology and Endocrinology 2004, 2:51 doi:10.1186/1477-7827-2-51

Published: 5 July 2004

Abstract

The prolactin (PRL) and growth hormone (GH) gene families represent species-specific expansions of pregnancy-associated hormones/cytokines. In this review we examine the structure, expression patterns, and biological actions of the pregnancy-specific PRL and GH families.