Table 1
Gene
 Expression per testis (relative to Luciferase × 103)
 GnRH-null relative to adult normal (corrected for cell number)2



Adult GnRH-null
 Adult normal
 Neonatal normal1
P450scc
 0.23 ± 0.04
 242 ± 35
 2.2 ± 0.5
 0.95%
P450c17
 15.3 ± 1.8
 3453 ± 1042
 13.5 ± 3.5
 4.4%
GST5-5
 60.6 ± 5.6
 677 ± 91
 76 ± 15
 89.5%
RLF
 19.2 ± 2.1
 2490 ± 611
 5.3 ± 1.3
 7.7%
3βHSD I
 7.5 ± 1.7
 51 ± 10
 4.6 ± 1.8
 147.0%
Renin
 0.027 ± 0.012
 21.4 ± 3.5
 5.8 ± 0.9
 1.3%
EH
 18.5 ± 1.6
 996 ± 112
 8.0 ± 1.6
 18.5%
StAR
 2.08 ± 0.2
 177 ± 30
 4.0 ± 1.1
 11.7%
3βHSD VI*
 0.014 ± 0.005
 124 ± 15
 ND3
 0.11%
PGD-synthetase*
 0.26 ± 0.06
 843 ± 43
 2.5 ± 1.1
 0.31%
EST*
 0.014 ± 0.009
 9.0 ± 2.4
 ND3
 1.5%
17βHSD III*
 2.39 ± 0.21
 1644 ± 192
 140 ± 7
 1.45%

* Genes expressed in adult Leydig cells but not fetal Leydig cells 1Neonatal animals were 5 days old. 2 Expression in GnRH-null mice is expressed as a percentage of normal mice and corrected for reduced Leydig cell number in GnRH-null animals [4]. 3ND = not detectable.

Baker et al. Reproductive Biology and Endocrinology 2003 1:4   doi:10.1186/1477-7827-1-4