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Advantages and disadvantages of the conventional swim-up method. |
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| Advantages |
Disadvantages |
|
|
|
| - easy to perform |
- restricted to ejaculates with high sperm count and motility |
| - very cost-effective |
|
| - usually recovery of a very clean fraction of highly motile spermatozoa |
- low yield |
| - spermatozoa can be massively damaged by reactive oxygen species |
|
| - significant decrease of the percentage of normally chromatin-condensed spermatozoa |
|
Henkel and Schill Reproductive Biology and Endocrinology 2003 1:108 doi:10.1186/1477-7827-1-108 |
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